On Aristophanes Knights 413

Aristophanes on Tragedy

Fifty years before Aristotle wrote his Poetics, Aristophanes had devoted two comedies, Thesmophoriazusae (411) and Frogs (405), to the subject of tragedy. In both plays the plot shows the education of the main character in the nature of tragedy. Euripides learns in Thesmophoriazusae that he must present noble and not base women in his dramas. His depiction of perverse women in the theatre had m...

The Ionian at Aristophanes

Acceleration of the Boundary Element Library BEM4I on the Knights Corner and Knights Landing Architectures

The aim of the poster is to present the acceleration of the boundary element method (BEM) by the Intel Xeon Phi technology. The poster provides brief overview of BEM followed by the discretization approach and efficient numerical assembly of the BEM matrices. We discuss its parallelization by OpenMP in shared memory and the SIMD vectorization necessary to exploit the full potential of the Xeon ...

Jgp_201711777 413..416

By tracking conformational transitions of individual ion channel proteins, single-channel recordings allow the observer to deduce gating mechanisms, as well as estimate rate constants of microscopic gating steps. For most ion channels, gating mechanisms are complex, comprising multiple stable open (O) and closed (C) conformations among which conformational transitions may follow a network of po...

Dmd048009 406..413

The pregnane X receptor (PXR) has been postulated to play a role in the metabolism of a-tocopherol owing to the up-regulation of hepatic cytochrome P450 (P450) 3A in human cell lines and murine models after a-tocopherol treatment. However, in vivo studies confirming the role of PXR in a-tocopherol metabolism in humans presents significant difficulties and has not been performed. PXR-humanized (...